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KMID : 0364219890320040322
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Korean Journal of Zoology
1989 Volume.32 No. 4 p.322 ~ p.328
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Effects of Carnitine on the Lipid Metabolism in the Ethanol-Fed Rats
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Choi Kyung-Hee
Hah Jae-Chung
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Abstract
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The effect of dietary carnitine on ethanol-induced fattv liver and hvpertriglyceridemia was examined in an animal model. Consistent with literature, ethanol fed at 5g/Kg of b.w. to rats produced a significant increase in hepatic concentrations of total lipid, kislycerine, phospholi-pid, free cholesterol and esteriaed cholesterol as well as elevated plasma concentrations of triglvceride. It was when the ethanol diet was supplemented with D.L. camitine that there was a singini-cant reduction in the accumulation of lipids in the ethanol-compromised liver. Dietary cacti-tine was also effective in ameliorating ethanol-induced hypeuriglyceridemia. Total protein con-tents in the plasma was not varied among the groups.
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KEYWORD
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Lipid metabolism , Ethanol Carnitine , Rat liver
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